Pharmacogenetical Variants in Whole-Genome Data
Name
Kevin Kanarbik
Abstract
Human DNA sequencing is becoming easier and cheaper. This makes simpler conducting a wide range of sequencing projects. These can help compare genetic data from different geographical populations. Pharmacogenetic variants are genetic elements that iscientific studies have linked to effects on drug metabolisation. All genetic variants including pharmacogenetic variants show some between-population frequencies. The main aim of this bachelor’s thesis is to describe pharmacogenetic variants that appear in the Estonian population and to use pharmacogenetic variant frequencies from whole-genome sequencing data of Estonian Genome Center in order to describe similarities and differences in various populations.
Graduation Thesis language
Estonian
Graduation Thesis type
Bachelor - Computer Science
Supervisor(s)
Tõnis Tasa
Defence year
2017